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cbd oil for migraines and anxiety

Can CBD Oil Treat a Migraine?

Nicholas R. Metrus, MD, is a board-certified neurologist and neuro-oncologist. He currently serves at the Glasser Brain Tumor Center in Summit, New Jersey.

With the laws governing the legal use of medical marijuana beginning to loosen up, there’s quite a bit of focus on the use of CBD oil—a component of the marijuana plant—for treating everything from arthritis to chronic pain, including migraines. But what is CBD oil, and does it really work to relieve migraine headaches?

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Verywell / Ellen Lindner

Cannabidiol (CBD) is just one of over 100 different substances found in the the Cannabis sativa plant. The portion of the cannabis plant that produces a high (the psychotropic effect) is called tetrahydrocannabinol, or THC. Depending on how it’s processed, CBD oil contains very little (or is completely void of) THC.  

Due to the pervasiveness and debilitating effects of migraine headaches, there’s been a lot of clinical research aimed at trying to find an effective treatment to minimize the frequency of migraines and alleviate the pain.

Medical experts currently consider the pain from a migraine headache the result of intense stimulation to sensory nerves—a response to inflammatory agents which are released when a migraine occurs. This would explain why powerful analgesic and anti-inflammatory agents, such as CBD oil, may be effective in the treatment of migraines.  

Properties of CBD Oil That Relieve Migraine

  • Potent analgesic (pain relieving) properties
  • Antiemetic (preventing nausea and vomiting) properties
  • Powerful anti-inflammatory effects  

CBD oil has gotten a lot of attention for its powerful pain-relieving properties, particularly since cannabis use is becoming legal in many states (33 as of October 2019, according to the National Conference of State Legislatures, but details vary). In June 2018, the FDA approved CBD for the first time for a new seizure medication called Epidiolex (cannabidiol) [CBD] oral solution.


According to a study published in Frontiers in Pharmacy, while there are many experts who advocate for the use of CBD oil for migraines, there is still not enough evidence to prove that treatment will CBD oil will be completely effective for alleviating migraine headaches.

The researchers add that given time, as the legalities around medical marijuana and CBD oil change, more research may be able to show that CBD oil works well enough and consistently enough to treat migraines.

“Cannabinoids—due to their anticonvulsive, analgesic, antiemetic, and anti-inflammatory effects —present a promising class of compounds for both acute [short-term, severe] and prophylactic [preventative] treatment of migraine pain,” explained lead study author Pinja Leimuranta, of the University of Eastern Finland. Although the researchers say that we are not completely there yet, they add that CBD oil can “absolutely help relieve some symptoms related to migraines.”  

While few clinical research studies have examined the use of CBD to treat migraines, a 2016 study, published in Pharmacotherapy, found that the frequency of migraines was reduced from nearly 10 per month to only approximately four per month in a group of medical marijuana users.   Research presented in 2017 at the Congress of the European Academy of Neurology showed that cannabinoids might help prevent migraines as well as easing the pain of migraine headache.

Additionally, a 2017 review of cannabis treatment for headaches outlined existing research, patient surveys, and case reports showing the efficacy of cannabis for migraine and other headache disorders.   A 2018 review described experimental evidence for the use of cannabinoids in the treatment of migraine as well as other headaches and chronic pain.

Uses and Safety

Previous research studies have shown that CBD oil, unlike THC, does not cause a euphoric high or psychotropic effects, and is typically less controversial and safer for medicinal use. CBD oil has been shown, in a limited number of studies, to be effective in the treatment of many disorders, including diabetes, arthritis, multiple sclerosis, and migraines.  

The type of cannabis that CBD is composed of is well tolerated and safe in humans. In one study, when cannabis with THC was given to study subjects, they experienced an increased heart rate, anxiety, and psychotic symptoms. However, participants who took CBD oil—lacking THC—did not experience side effects (including psychotic symptoms).  

Should You Use It?

Anyone considering the use of CBD oil for migraines should consult with their healthcare provider before taking it. It’s important to note that not all sources of the product are reputable.

Prescription drugs with CBD do not have any THC at all. But many over-the-counter CBD oil products, such as those sold online, contain trace amounts of THC.  

Another important action step to take before deciding to use CBD oil is to check to ensure that it is legal in your home state. Many states still consider even the prescribed use of CBD oil illegal, due to its link to marijuana. And the FDA has not approved any CBD products (prescription or over-the-counter), aside from Epidiolex.

This certainly does not indicate that people with migraines should stop searching for an effective treatment to alleviate pain and discomfort, nor should they give up hope. There are many proven effective solutions available for those who suffer from migraine headaches.

Find out what the most recent research says about the safety and effectiveness of CBD oil for migraines.

Best CBD Oil For Migraines & Headaches – 2021 Reviews

Best CBD oil for migraine

Migraines can make it difficult to participate in different activities. The constant thumping in your head can make it difficult to concentrate and can even cause nausea, chronic pain, and other symptoms that are difficult to manage with the standard treatment of migraines. Medical marijuana has a long history of use as a powerful painkiller, but CBD oil seems to offer more extended benefits and acting as an endocannabinoid system reuptake inhibitor. The compound produces many of the positive health effects associated with marijuana, but without the narcotic side effects. Hence, that’s why we researched the best CBD oil for migraines.

That’s where cannabinoid oil comes into play because it may reduce the strength of the cells located in the brain that cause migraine pain. Taking CBD oil can help sufferers eliminate the pain they feel for months on end.

In this article, we have found the top best cbd oil for migraine options that are sure to get you results. Each offers incredible return policies so that you are able to choose the right dosage for all of your needs!

The CBD Oil For Migraines & Headaches (April. 2021)

  • Royal CBD – Editor’s Pick
  • CBD Pure – Best Full Spectrum
  • Spruce CBD – Best Potency
  • Penguin CBD – Best Quality
  • CBDfx – Best Organic
  • Joy Organics – Best Value

CBD oil for migraines & anxiety

There is no scientific evidence or research on medical marijuana as an effective treatment for migraine and anxiety—in large part because it has not been formally studied. However, it may still be a viable topical option for some patients with joint and muscle pain associated with migraines. “If you have a lot of neck pain or soreness, it is perfectly reasonable to use CBD. It may even prevent nausea and vomiting,” Dr. Silberstein says.

There is proof that Cannabinoid oil can lessen inflammation and pain in inflammatory disease. it should work similarly with migraines. In a review of studies, published in 2017, researchers saw a helpful and effective role for marijuana in treating migraine, however, there are not enough studies on using CBD specifically yet.

As the studies come in examining the effectiveness and side effects of their product, there will be further changes in laws and recommendations. Both the causes of migraines and the potential results of CBD stay unclear. A lot of studies specific to the elements of marijuana, like CBD, are necessary.

CBD oil has received plenty of praise recently from individuals touting its ability to alleviate and even stops the pain caused by migraine headaches. Simply take a look at the popular online message board Reddit to check that there are lots of people that swear by its all-natural healing power. Some customers even state to have experienced relief from their migraines by using topical CBD products by applying them to temples, jaw, or neck muscles.

People who suffer from migraines, it’s simple to get excited hearing regarding new effective treatment that has been good and effective for others, however, you should thoroughly research at new rising trends to check if the proof is really there, or if it’s simply more hype. Unfortunately, this could be tough to do when it comes to using CBD because of a lack of adequate research, and contraband laws in some locations.

The research some experts do have regarding the results of CBD oil on migraines is positive. unfortunately, because of the legal status of cannabidiol, adequate analysis for CBD specific effective treatment is still lacking mostly because of the very fact that there are currently more studies being done on medical marijuana. As a result, patients are typically forced to have faith in self-reports when it comes to CBD.

Spruce 750 MG Full Spectrum CBD Oil

Spruce CBD

Why is it better?

  • Organic Ingredients
  • Full-Spectrum
  • Third-party Lab Tested

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Top 4 Best CBD Oil for Migraines Reviews

Spruce CBD – Editor’s Pick

Spruce 750 MG Full Spectrum CBD Oil

Users of CBD should pay attention to Spruce CBD for its effective results, high potency, organic ingredients, and product lines of lab quality. They are striving for no-frills, only for quality.

  • Organic, vegan, and gluten-free
  • Third-party lab tested
  • Ships to all 50 States
  • Low transparency
  • Small product range

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Spruce is a new brand but they are gradually building their own stable space. They are committed to selling high-quality CBD products. It has a handful of items and guarantees that they are of the best.

Spruce uses just 100% of natural ingredients derived from local and organically cultivated hemp. Since they have full-spectrum CBD oil, taking CBD products from them may have cannabinoids along with CBDs such as CBC, CBN, and even a THC whiff.

Taking CBD products from Spruce may not only treat pain but also, their CBD oil may be one of the best CBD oil for migraines.

Penguin CBD – Best in the Market

penguim cbd oil-3

Penguin is a growing company but appears to be serious regarding CBD. It gets its cannabis plant or hemp from Oregon growers and exceeds current quality standards.

  • Third-party lab tested
  • Good quality of CBD products
  • No international shipping
  • No lower potency options

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The team behind Penguin CBD formed the company. They all came from a variety of cultures, professions, and fields of education. But at its core, they believe in the extraordinary quality of hemp to restore equilibrium and enhance wellness.

Their website is straight to the point without a lot of detail. Just the facts and manufacturing process is described in this manner. Penguin uses the CO2 extraction method to extract CBD from hemp.

It’s important to know what kind of CBD products you need to treat your pain related to migraines. Therefore you might want to try their CBD oils.

Although CBD oil has been found to have only a low risk of side effects, it is still important to check with your doctor or medical advice before starting a CBD oil regime.

Pure CBD Oil – Best Full Spectrum

CBDPure CBD Oil_1

Pure CBD has a small variety of products. They presently supply five CBD products, which are gummies, oils. Every product lists the quantity of CBD per serving or use.

  • Organic-grown hemp
  • Affordable prices
  • No international shipping
  • Some product have sweeteners

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Sunday Scaries is a California-based company founded back in 2017. Its founders – Mike Still and Beau Schmitt, have decided to found Sunday Scaries after having tested the effects of CBD oil on themselves. Mike and Beau have been friends for a long time, a mutual friend of theirs introduced them to wonderous of CBD.

The Sunday Scaries CBD oil may help each individual who suffers migraine pain. It is proven that using their products as treatment of migraine can give better results than other brands. Their extensive third-party lab research results allow you to be sure that they are a trustworthy brand.

Numerous research and studies conducted in this product provide positive results as a treatment of migraine pain and may give more beneficial effects. Although few individuals comment about the side effects of CBD, the company is proven to give fast and trustworthy results with the use of medical marijuana.

Royal CBD – Best Potency

royal cbd oil

Royal CBD is a company that seeks to improve the quality of the wellbeing of its consumers in a way that would not threaten their safety or their health. Additionally, they are based in California.

  • Third-party lab tested
  • Supercritical CO2 extraction
  • Limited Options

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The brand acquires its CBD oil from organic and GMO-free hemp which is grown without harmful chemicals and pesticides being used. This is essential in fact because hemp is known as a bio-accumulator.

This means hemp is capable of removing all the chemicals and compounds from the soil. Royal CBD only offers products with full-spectrum CBD. This helps you to enjoy the advantages of cannabidiol to the fullest.

Those migraine sufferers may not only choose full-spectrum CBD since the brand also offers broad-spectrum CBD which may help with migraine headaches. Royal CBD may only be one of the best CBD oil.

What Are Migraines?

A study about Migraines explains that it is a recurring type of headache. They cause moderate to severe pain which pulses or throbs. Mostly, the pain lies on one side of your brain and you may have other symptoms including nausea and fatigue. It would seem that you will be sensitive to sound and light.

There are four distinct migraine stages. Whenever you have a migraine you can not always go through every step.

  • Prodrome. It begins up to 24 hours before you experience the migraine. You have symptoms and signs like cravings for food, unexplained shifts in mood, uncontrollable yawning, fluid retention, and excessive urination.
  • Aura. You can see flickering or bright lights, or zig-zag lines if you have this phase. You can have muscle weakness, or feel squeezed or caught. An aura can occur just prior to or during a migraine.
  • Headache. A migraine normally starts slowly and then gets serious. Typically it induces throbbing or pulsing pain that is mostly on one side of the brain. But you will get a migraine even without a headache. Other symptoms may include:
    • Greater sensitivity to glare, noise, and smells
    • Nausea and nausea
    • Worsened pain when you pass, sneeze, or cough
  • Postdrome (following the headache).After a migraine, you may feel tired, sick, and confused. That can last for up to one day.

Migraines are more prominent in the morning; people also wake up. Several people get migraines at regular times, for example before menstruation, or on weekends after a busy work week.

People define migraine pain as:

  • Pulsating
  • Throbbing
  • Perforating
  • Pounding
  • Debilitating

It can also feel like a dull, constant, serious ache. The pain may start as mild but it will get moderate to an extreme without treatment. Migraine pain most often affects the region of your forehead. Typically it’s on one side of the head but it can happen on both sides or change.

The majority of migraines last about four hours. They can stay for as long as 72 hours to a week if they are not treated or don’t respond to treatment. In migraines with aura, pain may coincide with an aura, or it may never occur.

Does CBD Help with Migraines?

Research published in Frontiers of Neurology in 2018 examined evidence that CBD oil has numerous beneficial pharmacological effects, including as an anti-inflammatory, antioxidant, antiemetic, antipsychotic, and neuroprotective drug. CBD oil has been studied for the treatment of diabetes, depression, arthritis, and other conditions.

The study additionally indicates the fact that CBD is beneficial as it has no side effects that can affect heart rate, blood pressure, body temperature, and psychomotor and psychological motion is not negatively affected.

While there are still no clinical trials examining the effectiveness of CBD oil as a migraine cure, numerous academic reviews and research point to the significance of modulating the endocannabinoid system (ECS) and using cannabinoids like CBD as a possible therapy.

Endocannabinoid system receptors are found in the pain-processing areas of the brain. In animal models, CBD may lessen inflammation and pain by specifically targeting receptors inside the endocannabinoid system.

For those people who want to try CBD oil products like full-spectrum CBD oil, capsules, and more to improve their immune system or treat migraines. Be sure to check that every CBD oil and products are from legal sellers approved by FDA and undergoes the third lab tests. You may also consult your doctor before purchasing any CBD products

How to apply cbd oil for headaches

Although lawmakers in the United States are currently debating the merits of cannabis and related products, the plant’s medicinal uses aren’t a new discovery.

According to the National Center for Complementary and Integrative Health (NCCIH), cannabis has been used in alternative medicine for over 3,000 years. Some of these treatments involve the management of pain, neurological symptoms, and inflammation.

CBD oil can be used through:

  • Vaping
  • Ingestion
  • Applied topically

Oral CBD oil is most likely to not cause side effects than vaping, so some new users may want to start there. You can:

  • Put a couple of drops of oil below your tongue
  • Take CBD capsules
  • Eat or drink a CBD-infused treat
  • Vaping CBD oil very much useful if you’re experiencing a severe migraine at home and you don’t have to leave and go elsewhere.

The National Cancer Institute (NCI) explains that the inhalation process delivers the compounds to your bloodstream much quicker than other methods. Currently, there aren’t any formal tips for correct dosing for a migraine attack. Work along with your doctor to see the proper dosage.

If you’re new to CBD, you must start with the lesser dosage possible. You can bit by bit work your way up to the full recommended dose. this can allow your body to get used to the oil and cut back your risk of side effects of cbd.

Potential Risks & Side Effects

Using CBD oil also brings with it certain risks. While often well-tolerated, CBD oil can cause side effects such as dry mouth, diarrhea, decreased appetite, drowsiness, and fatigue. Also, CBD can interact with other medications you take, such as blood thinners.

In clinical trials, the FDA rights reserved, for young people between the ages of 2 and 18, high regular doses of CBD were given for 14 weeks. The daily doses were equivalent to 1,360 mg for those of 150 pounds, more than is commonly found in a whole bottle of oil.

These are the side effects they most often experienced:

  • Tiredness
  • Decreased appetite
  • Gastrointestinal problems
  • Altered liver enzymes

For several patients, these side effects occurred during the first few weeks, as their oil dosage was rapidly increased. Usually, the symptoms died down once their dosage normalized, and reducing the dose was indeed an effective way to decrease unwanted side effects. If you encounter any one of these side effects on your existing CBD, you may also want to try with waiting for it a week, decreasing your daily dosage, or totally testing out a different type of CBD product.

Frequently Asked Questions

Contact our support system that’s available for live discussions that will help you make the best CBD oil choice for you and your needs.

Since pain is the most unwanted side effects of tension headaches, the cannabinoid oil works with the endocannabinoid system to suppress the nerves in the brain that cause painful headaches. Taking CBD oil can relieve this unwanted symptom while actively promoting a healthy mood, immune response, and an overall sense of well-being.

Follow the dosing instructions that are located on the bottle and if that dosage doesn’t work increase the dosage slowly every 1-2 weeks. Do you feel better? Have you noticed any side effects? Slowly start increasing your dose every three or four days, constantly checking in with yourself to see if you feel any changes. Again, changes tend to take time to develop, so patience is required.


  • nStephen D. Silberstein (2015). Preventive Migraine Treatment

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There are a number of tips that people give you on how to reduce a migraine. Try using the best CBD oil for migraines in 2021.