How Does CBD Make You Feel and Can It Get You High?
- Does CBD get you high?
- How does CBD make you feel?
- Can CBD make you fail a drug test?
CBD is a compound found in cannabis plants (a cannabinoid) that provides proven therapeutic benefits. Because it doesn’t have the same intoxicating effects as its cannabinoid cousin tetrahydrocannabinol (THC), cannabidiol (CBD) is more lightly regulated, and can be sold without a prescription in most U.S. locations. Even high CBD strains of cannabis can be purchased online without a medical marijuana card.
Both hemp and marijuana are the same species of plant—Cannabis sativa—but hemp has been selectively bred for thick, heavy stalks, whose fibers have been used for centuries to make clothing, sails, paper and rope. Since most of the THC in cannabis is found in the flowering portions of the plant, marijuana breeders have sought plants with lush, heavy flowers (buds), and for decades have selectively bred out the CBD, which moderates the racy high of THC.
CBD has psychoactive effects too. But whether you call CBD’s effects a high or not, vaping it or using CBD oil makes you feel different. There are noticeable sensations that many users find as pleasant as those provided by THC. Unlike THC products though, using pure (or nearly pure) CBD will not make you fail a drug test—as long as you’re careful to choose the right kinds of CBD products.
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Does CBD get you high?
Both CBD and THC are mood-altering compounds that have significant therapeutic benefits, like relieving pain and nausea, reducing inflammation, and treating some seizure disorders. But even though both cannabinoids are psychoactive, only THC is intoxicating. While CBD promotes relaxation and calmness, THC produces actual euphoria, and alters perceptions of space and time.
How does CBD work?
Humans and other mammals have an internal network of chemicals and receptors in the central and peripheral nervous systems called the endocannabinoid system. These receptors, named CB1 and CB2, bind with molecules called ligands (in this case endogenous cannabinoids like anandamide) to control the release of neurotransmitters like glutamate and dopamine. The endocannabinoid receptors, ligands, and certain enzymes work in concert to affect a variety of processes in the body, including thought, memory, mood, pain management, and appetite.
Cannabinoids created outside the body—called exogenous cannabinoids—like CBD and THC from the cannabis plant, can also bind with the CB1 or CB2 (and other) receptors to produce various effects and moderate some physical functions. THC can relieve nausea and increase appetite, and both CBD and THC are effective for pain relief. CBD is an antioxidant and an anti-inflammatory, and has proven medically effective in treating certain seizure disorders.
Cannabinoids like CBD and THC are not considered dangerous, because they don’t affect the parts of the brain that regulate vital functions of the body. Unlike opioid receptors, the cannabinoid receptors will never signal your lungs to stop breathing. For this reason, it’s practically impossible to overdose on cannabis.
Is CBD psychoactive or intoxicating?
CBD is thought to be helpful in treating anxiety and insomnia. And while the scientific research isn’t absolutely clear, anxiety, stress and sleep problems are the most common reasons consumers use CBD. For many people, CBD is relaxing.
Interestingly, marijuana strains that have significant quantities of both CBD and THC rarely produce the undesirable effects—like paranoia and anxiety—sometimes experienced with weed that’s high in THC but has low CBD content. CBD apparently “competes” with THC on the CB1 receptors, and thereby moderates the psychological effects of its racier relative.
Although CBD may alter your mood—providing a deep sense of calm and relaxation—it doesn’t change spatial and sensory perception or create euphoria, like THC does. In that sense, both cannabinoids are psychoactive, but only THC is intoxicating. This also applies to delta 8 products, THCA and all other forms of tetrahydrocannabinol.
How does CBD make you feel?
As we’ve already discussed, CBD’s primary sensation is relaxation. People describe it sometimes in terms of neutralizing pain and discomfort, or removing stress. For some, that feels like an effect in itself. For others, it’s an exaggerated sense of peace and calm, or just a lack of whatever negative feelings they had experienced before.
Because CBD is an anti-inflammatory, it can reduce pain and relax the body. That, along with the stress and anxiety relief, may be noticeable. A first-time user of CBD tincture and CBD capsules told Vaping360 that he felt “super relaxed, no anxiety, no pain, and almost like I was floating.”
People who vape or smoke CBD-rich hemp flowers (buds) or high-CBD/low-THC marijuana flowers seem to experience the most obviously psychoactive effects. That may be because the flower contains a higher level of THC than other CBD products.
A high-CBD cannabis flower user on Reddit described “an effect” that “could be described as an anti-effect.” They said that “something happens and things seem to lift away with no feeling.” A Vaping360 editor says that CBD “both dulls and clarifies your mental state. Either way, your mental state can be altered.”
Vaping and smoking expedite the active ingredients to the brain (through the lungs) much more quickly than other delivery methods. Using CBD oil tinctures sublingually (under the tongue) is the second-fastest method (though still much slower than inhalation). Using CBD edibles or swallowing a tincture is the slowest, since the CBD must process through the liver before reaching the bloodstream and brain.
It’s possible that some users feel the presence of any amount of THC when it’s mixed with CBD. That’s the well-known “entourage effect” theory, which basically says cannabinoids combine to create more than the sum of their parts. It’s worth experimenting with different kinds of CBD products to see what feels best to you.
In addition to CBD-rich flowers, CBD can be consumed in vape juice (e-liquid), CBD oil tinctures, edible products like gummies and drinks, in capsules, and in a wide variety of topical lotions and creams. CBD e-juice can be vaped in a regular vape mod or pen, or taken orally like a tincture. But even if its label calls CBD e-liquid “oil,” it isn’t really oil; e-liquid is made with propylene glycol and vegetable glycerin. Tinctures are made with actual CBD oil and carrier oils like MCT or coconut oil, and can only be consumed orally, never vaped. Inhaling real oils can be dangerous.
One product to avoid is CBD oil that has been adulterated with synthetic cannabinoids. These are lab-created chemical compounds that bind with the same cannabinoid receptors in the brain that THC and CBD do. But they can be as much as 100 times more powerful than THC, and have been known to cause extended psychotic episodes and even death. They’re often sold under the brands Spice and K2 (but there are many others) in truck stops, head shops and convenience stores. Sometimes they’re sold as vape juice in bottles marked CBD.
Avoiding synthetic cannabinoids—or other less-sinister additives you don’t want, like melatonin—is simple. Buy from reputable dealers who offer a third-party chemical analysis of the products they sell. That’s something you may want to do anyway if you’re concerned that the CBD oil you buy could make you fail a drug test.
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Can CBD make you fail a drug test?
CBD is extracted from hemp and processed into different kinds of CBD products. CBD isolate and broad-spectrum CBD contain no discernible THC, and are the safest ways of using CBD if you are concerned about a drug test. Full-spectrum CBD contains traces of THC, and although it too is unlikely to make you fail a test, it should probably be avoided to be absolutely sure.
CBD derived from hemp plants almost always contains less than 0.3% THC, which is the legal maximum it can include unless it’s sold by a licensed dispensary in a state with a legal marijuana market. You can verify how much THC a product contains by checking the third-party test on the manufacturer’s website. If the seller can’t produce a test, or you feel hesitant, move on to a different company.
Hemp-derived CBD oil is highly unlikely to make you fail a drug test. As long as the CBD you choose has been tested by a third party, and is sold by a reputable retailer that stands behind its products, you can use it with confidence and enjoy the benefits CBD offers.
CBD is often thought of as the non-psychoactive cannabinoid, but even though CBD is not intoxicating, it does have physical and psychological effects.
What Are the Benefits of CBD?
More than 60 percent of CBD users were taking it for anxiety, according to a survey of 5,000 people. Does it help?
By Dawn MacKeen
The CBD industry is flourishing, conservatively projected to hit $16 billion in the United States by 2025. Already, the plant extract is being added to cheeseburgers, toothpicks and breath sprays. More than 60 percent of CBD users have taken it for anxiety, according to a survey of 5,000 people, conducted by the Brightfield Group, a cannabis market research firm. Chronic pain, insomnia and depression follow behind. Kim Kardashian West, for example, turned to the product when “freaking out” over the birth of her fourth baby. The professional golfer Bubba Watson drifts off to sleep with it. And Martha Stewart’s French bulldog partakes, too.
What is CBD?
Cannabidiol, or CBD, is the lesser-known child of the cannabis sativa plant; its more famous sibling, tetrahydrocannabinol, or THC, is the active ingredient in pot that catapults users’ “high.” With roots in Central Asia, the plant is believed to have been first used medicinally — or for rituals — around 750 B.C., though there are other estimates too.
Cannabidiol and THC are just two of the plant’s more than 100 cannabinoids. THC is psychoactive, and CBD may or may not be, which is a matter of debate. THC can increase anxiety; it is not clear what effect CBD is having, if any, in reducing it. THC can lead to addiction and cravings; CBD is being studied to help those in recovery.
Cannabis containing 0.3 percent or less of THC is hemp. Although last year’s Farm Bill legalized hemp under federal law, it also preserved the Food and Drug Administration’s oversight of products derived from cannabis.
What are the claims?
CBD is advertised as providing relief for anxiety, depression and post-traumatic stress disorder. It is also marketed to promote sleep. Part of CBD’s popularity is that it purports to be “nonpsychoactive,” and that consumers can reap health benefits from the plant without the high (or the midnight pizza munchies).
Just as hemp seedlings are sprouting up across the United States, so is the marketing. From oils and nasal sprays to lollipops and suppositories, it seems no place is too sacred for CBD. “It’s the monster that has taken over the room,” Dr. Brad Ingram, an associate professor of pediatrics at the University of Mississippi Medical Center, said about all the wild uses for CBD now. He is leading a clinical trial into administering CBD to children and teenagers with drug-resistant epilepsy.
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Does CBD work?
“It’s promising in a lot of different therapeutic avenues because it’s relatively safe,” said James MacKillop, co-director of McMaster University’s Michael G. DeGroote Center for Medicinal Cannabis Research in Hamilton, Ontario.
Last year, the F.D.A. approved Epidiolex, a purified CBD extract, to treat rare seizure disorders in patients 2 years or older after three randomized, double-blind and placebo-controlled clinical trials with 516 patients that showed the drug, taken along with other medications, helped to reduce seizures. These types of studies are the gold standard in medicine, in which participants are divided by chance, and neither the subject nor the investigator knows which group is taking the placebo or the medication.
While there is hope for treating other conditions with the plant extract, Epidiolex remains the only CBD-derived drug approved by the F.D.A. Most of the research on cannabidiol has been in animals, and its current popularity has outpaced science. “We don’t have the 101 course on CBD quite figured out yet,” said Ryan Vandrey, an associate professor of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine.
Does CBD help anxiety and PTSD?
For students with generalized social anxiety, a four-minute talk, with minimal time to prepare, can be debilitating. Yet a small experiment in the journal Neuropsychopharmacology found that CBD seemed to reduce nervousness and cognitive impairment in patients with social anxiety in a simulated public speaking task.
However, a double-blind study found healthy volunteers administered CBD had little to no change in their emotional reaction to unpleasant images or words, compared to the placebo group. “If it’s a calming drug, it should change their responses to the stimuli,” said Harriet de Wit, co-author of the study and a professor in the University of Chicago’s department of psychiatry and behavioral neuroscience. “But it didn’t.”
Many soldiers return home haunted by war and PTSD and often avoid certain activities, places or people associated with their traumatic events. The Department of Veterans Affairs is funding its first study on CBD, pairing it with psychotherapy.
“Our top therapies attempt to break the association between reminders of the trauma and the fear response,” said Mallory Loflin, an assistant adjunct professor at the University of California, San Diego and the study’s principal investigator. “We think that CBD, at least in animal models, can help that process happen a lot faster.” While large clinical trials are underway, psychologists say there isn’t compelling evidence yet as to whether this is a viable treatment.
Does CBD help sleep and depression?
Up in the wee hours of the night, stuck watching videos of puppies? CBD may be promising as a sleep aid; one of the side effects of the Epidiolex trials for epilepsy was drowsiness, according to Mr. MacKillop, a co-author of a review on cannabinoids and sleep. “If you are looking for new treatments for sleep, that may be a clue,” he said.
But he cautions that the side effects could have been because of an interaction with other medications the children were taking to control the seizures. So far, there hasn’t been a randomized, placebo-controlled, double-blind trial (the gold standard) on sleep disorders and CBD.
A recent chart review of 72 psychiatric patients treated with CBD found that anxiety improved, but not sleep. “Over all, we did not find that it panned out as a useful treatment for sleep,” said Dr. Scott Shannon, assistant clinical professor of psychiatry at the University of Colorado, Denver and the lead author of the review in The Permanente Journal.
Sleep can be disrupted for many reasons, including depression. Rodents seemed to adapt better to stressful conditions and exhibited less depressive-like behavior after taking CBD, according to a review in Journal of Chemical Neuroanatomy. “Surprisingly, CBD seems to act faster than conventional antidepressants,” wrote one of the authors of a new review, Sâmia Joca, a fellow at the Aarhus Institute of Advanced Studies in Denmark and an associate professor at the University of São Paulo in Brazil, in an email interview. Of course, it’s difficult to detect depression in animals, but the studies that Ms. Joca and her colleagues reviewed suggested that in models of chronic stress exposure, the mice and rats treated with CBD were more resilient.
But without clinical trials in humans, psychologists say CBD’s effect on depression is still a hypothesis , and not an evidence-based treatment.
Is CBD harmful?
“If you take pure CBD, it’s pretty safe,” said Marcel Bonn-Miller, an adjunct assistant professor at the University of Pennsylvania’s Perelman School of Medicine. Side effects in the Epidiolex trial included diarrhea, sleepiness, fatigue, weakness, rash, decreased appetite and elevated liver enzymes. Also, the safe amount to consume in a day, or at all during pregnancy, is still not known.
Recently, the F.D.A. sent a warning letter to Curaleaf Inc. about its “unsubstantiated claims” that the plant extract treats a variety of conditions from pet anxiety and depression to cancer and opioid withdrawal. (In a statement, the company said that some of the products in question had been discontinued and that it was working with the F.D.A.)
Dr. Smita Das, chair of the American Psychiatric Association’s Council on Addiction Psychiatry’s cannabis work group, does not recommend CBD for anxiety, PTSD, sleep or depression. With patients turning to these to unproven products, she is worried that they may delay seeking appropriate mental health care: “I’m dually concerned with how exposure to CBD products can lead somebody into continuing to cannabis products.”
Some CBD products may contain unwanted surprises. Forensic toxicologists at Virginia Commonwealth University examined nine e-liquids advertised as being 100 percent natural CBD extracts. They found one with dextromethorphan, or DXM, used in over-the counter cough medications and considered addictive when abused; and four with a synthetic cannabinoid, sometimes called Spice, that can cause anxiety, psychosis, tachycardia and death, according to a study last year in Forensic Science International.
Earlier research found fewer than a third of 84 products studied contained the amount of CBD on their labels. Some users of CBD have also failed drug tests when the product contained more THC than indicated.
This year, 1,090 people have contacted poison control centers about CBD, according to the American Association of Poison Control Centers. Over a third are estimated to have received medical attention, and 46 were admitted into a critical care unit, possibly because of exposure to other products, or drug interactions. In addition, concern over 318 animals poured into the American Society for the Prevention of Cruelty to Animals’ Animal Poison Control Center.
Is CBD a scam or not?
A few drops of CBD oil in a mocha or smoothie are not likely to do anything, researchers contend. Doctors say another force may also be at play in people feeling good: the placebo effect. That’s when someone believes a drug is working and symptoms seem to improve.
“CBD is not a scam,” said Yasmin Hurd, director of the Addiction Institute of Mount Sinai in New York City who led a double-blind study of 42 recovering heroin addicts and found that CBD reduced both cravings and cue-based anxiety, both of which can cycle people back into using. “It has a potential medicinal value, but when we are putting it into mascara and putting it into tampons, for God’s sake, to me, that’s a scam.”
More than 60 percent of CBD users were taking it for anxiety, according to a survey of 5,000 people. Does it help?