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I keep hearing about CBD oil. Is it safe to try?

Q: I keep hearing about CBD oil. Is it safe to try?

A: Cannabidiol (CBD) oil is popular for symptom relief in a number of ailments. While it’s mostly considered safe, it’s not without risks.

CBD is a chemical derived from Cannabis sativa (marijuana). CBD contains little or no delta-9-tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana that produces a high. The usual CBD formulation is oil, but CBD is also sold as an extract, vaporized liquid or oil-based capsule.

Reported uses for CBD include relief from:

  • Physical discomfort or chronic pain
  • Involuntary movements related to conditions such as amyotrophic lateral sclerosis and multiple sclerosis.
  • Insomnia
  • Symptoms associated with mental health conditions such as anxiety, bipolar disorder, schizophrenia and social phobia

While it’s generally well tolerated, CBD can cause side effects such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you’re taking, such as blood thinners. Another cause for concern is the unreliability of the purity and dose of CBD in products since they aren’t regulated. CBD products can also be quite expensive.

The only CBD product approved by the Food and Drug Administration is a prescription oil called Epidiolex. It’s approved to treat two types of epilepsy. Aside from Epidiolex, state laws on CBD vary. Some states place specific medical restrictions on who can purchase CBD products, while other states may allow people to obtain them openly at a dispensary or store.

If you plan to try products containing CBD, talk to your.

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Question and answer — I keep hearing about CBD oil. Is it safe to try?

Clinicians’ Guide to Cannabidiol and Hemp Oils

Affiliations

  • 1 Creighton University School of Medicine, Omaha, NE. Electronic address: [email protected]
  • 2 Section of Integrative Medicine and Health, Mayo Clinic, Rochester, MN.
  • 3 Division of General Internal Medicine, Mayo Clinic, Rochester, MN.
  • PMID: 31447137
  • DOI: 10.1016/j.mayocp.2019.01.003

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Clinicians’ Guide to Cannabidiol and Hemp Oils

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Authors

Affiliations

  • 1 Creighton University School of Medicine, Omaha, NE. Electronic address: [email protected]
  • 2 Section of Integrative Medicine and Health, Mayo Clinic, Rochester, MN.
  • 3 Division of General Internal Medicine, Mayo Clinic, Rochester, MN.
  • PMID: 31447137
  • DOI: 10.1016/j.mayocp.2019.01.003

Abstract

Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa that have become very popular over the past few years. Patients report relief for a variety of conditions, particularly pain, without the intoxicating adverse effects of medical marijuana. In June 2018, the first CBD-based drug, Epidiolex, was approved by the US Food and Drug Administration for treatment of rare, severe epilepsy, further putting the spotlight on CBD and hemp oils. There is a growing body of preclinical and clinical evidence to support use of CBD oils for many conditions, suggesting its potential role as another option for treating challenging chronic pain or opioid addiction. Care must be taken when directing patients toward CBD products because there is little regulation, and studies have found inaccurate labeling of CBD and tetrahydrocannabinol quantities. This article provides an overview of the scientific work on cannabinoids, CBD, and hemp oil and the distinction between marijuana, hemp, and the different components of CBD and hemp oil products. We summarize the current legal status of CBD and hemp oils in the United States and provide a guide to identifying higher-quality products so that clinicians can advise their patients on the safest and most evidence-based formulations. This review is based on a PubMed search using the terms CBD, cannabidiol, hemp oil, and medical marijuana. Articles were screened for relevance, and those with the most up-to-date information were selected for inclusion.

Copyright © 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa that have become very popular over the past few years. Patients report relief for a variety of conditions, particularly pain, without the intoxicating adverse effects of medical marijuana. In June 2018, the fir …